Freireich and Frei became unlikely partners when they went to work at the National Cancer Institute in 1955.  They were opposites in personality, but they were miracle workers on the leukemia ward. At that time the death rate for childhood leukemia was 90%.  Children were bleeding to death.  Freireich and Frei were first to do something about the falling levels of platelets in these children. Against resistance, when the NCI’s blood bank refused to give them blood for the necessary transfusions, they sought blood elsewhere. They got the blood, transfused the children and the results were notable. Freireich and Frei  decided that using multiple chemotherapy medications would be more effective than one medication at a time.  Again, they were seriously accused of being cruel to children. They went ahead with their idea. They started using a cocktail of four medications. Children began to survive. Unfortunately, eventually the cancer came back. Next Freireich and Frei decided that they needed to give their chemo cocktail for an entire year. Even though they had been so successful with their innovations, …